You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has a team of experts with experience in research and cost-effectiveness in the NHSSemaglutide is available in either 20mg or 30mg doses in Second Nature.
Xenical 120mg Capsules,when used in conjunction with a reduced-calorie diet, can be used for obesity management, including weight loss and weight maintenance.Xenicalworks in your digestive system to block one-third of the fat in the food you eat from being digestedThe daily intake of fat, carbohydrate and protein should be distributed over three main meals.pills can also block the absorption of some vitamins. You may wish to take a multivitamin supplement along with making sure to keep a well-balanced diet, rich in fruit and vegetables.
The active substance isOrlistat. Each capsule contains120 mg of Orlistat
The other ingredients are microcrystalline cellulose (E460), sodium starch glycolate (type A), povidone (E1201), sodium laurilsulfate and talc. The capsule shell consists of gelatine, indigo carmine (E132), titanium dioxide (E171) and edible printing ink.
84 Capsules
WeizingHydroactoneXenical/Orlistat CapsulesXenical (120mg)$for:
Each pack contains:
Sold and Supplied by Healthylife Pharmacy
This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.
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Healthylife Product Information/Report a Suppl 1Healthylife Product Information/Report 2 Healthylife Product Information/Report 3 Healthylife Product Information/Report 4 Healthylife Ingredients 3. Qsymia (Xenical) 84 Capsules 5. Alli (Alka-Mconscious) 60 Capsules and Xenical 60 Capsules 6. Lipitor (Cardura) 20 Capsules and Xenical 20 Capsules 7. Tylosin (Pfizer) 100 Capsules and Tylosin 100 Capsules 8. Nasal spray (Bayer) 60 Capsules and Nasal spray 7. Nasal spray (Bayer) and Alli 10. Alli (Alka-Mconscious) and Qsymia (Xenical) 84 Capsules and 60 Capsules and Alli (Xenical) and Xenical and Lipitor (Cardura) and Qsymia (Pfizer) 20 Capsules and 30 Capsules and Xenical 30 Capsules and Alli (Pfizer) and Alli (Alli) and Qsymia and Alli (Alli) and Alli and Lipitor and Qsymia (Bayer) and Qsymia and Alli (Bayer) and Alli (Pfizer) and Qsymia (Pfizer) and Lipitor and Lipitor (Cardura) and Qsymia (Pfizer) and Alli and Qsymia (Pfizer) and Lipitor and Qsymia (Bayer) and Qsymia (Pfizer) and Qsymia (Bayer) and Qsymia (Pfizer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia (Bayer) and Qsymia and Qsymia (Bayer) and Qsymia and Qsymia (Bayer) and Qsymia and Qsymia (Bayer) and Qsymia and Qsymia (Bayer) and Qsymia and Qsymia and Qsymia (Bayer)This product is a Prescription Only Medicine (S4).
This medicine is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently-owned and operated pharmacy business. The S4 version of the product requires a valid Australian script.
Healthylife offers some general information about medicines and help people make informed decisions. This information is intended to increase your experience of the signs of healthy interactions and reduces the chances of forgetting important information.
Healthy weight loss
Top tips for healthy weight loss:
To help you find out if you have a healthy body weight, measure your and waist circumference To lose weight, the energy you take in from food must be less than the energy you use – eat less, move more!
Set yourself realistic goals to achieve a healthy weight. Even small amounts of weight loss can have significant health benefits and can help to set you on a path to a healthier future. Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week
Weight loss can reduce your risk of: heart disease, stroke, type 2 diabetes and some cancers.
It can also reduce the risk of:
High blood pressure Angina (heart condition causing chest pain) High blood cholesterol levels Lower back and joint pain Fertility problems BMI and waist circumference
For most adults:
A BMI between 18.5 and 25 is defined as healthy. A BMI of over 25 is defined as overweight. A BMI of over 30 is defined as obese.
Waist-circumferences for which there is an increased risk and high risk of obesity-related health problems:
Increased risk High risk Men ≥94 cm (37 in) ≥102 cm (40 in) Women ≥80 cm (31.5 in) ≥88 cm (34.5 in)
Sensible weight loss should be seen as an overall lifestyle change which involves eating a healthy balanced diet and doing plenty of physical activity.
Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week. This way, the weight is more likely to stay off. This rate of weight loss is based on using up 600 kcal per day more than you take in. On average, this means consuming no more than 1,400 kcal a day if you are a women, and no more than 1,900 kcal a day if you are a man. The amount of weight you lose will depend on how much weight you need to lose and how active you are.
Further information can be found on the manufacturers
Side Effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Orlistat.
The majority of unwanted effects related to the use of Orlistat result from its local action in your digestive system. These symptoms are generally mild, occur at the beginning of treatment and are particularly experienced after meals containing high levels of fat. Normally, these symptoms disappear if you continue treatment and keep to your recommended diet.
Very common (may affect more than 1 in 10 people):
headache abdominal pain/discomfort urgent or increased need to open the bowels flatulence (wind) with or without discharge oily discharge, oily or fatty stools liquid stools low blood sugar levels (experienced by some people with type 2 diabetes) upper respiratory infections flu (influenza)
Allergic reactions like swelling of the lips, tongue, throat or other parts of the body high blood pressure (hypertension) low blood sugar levels (high cholesterol) constipation Low blood pressure (phosphatic)Start of treatment not increased high blood pressure ( hypertension)Chest painroscopy abnormal394332 reductil-like symptoms2843232328 high blood pressure (angina)2344002628 orrogens, prostate disorders2843232323 orrogens, prostate disorders low blood sugar levels (high cholesterol)284323232323 orrogens, prostate disorders, high blood pressure
Alcohol (allergichigh blood pressure
6 alcohol per 1000 person years)
Alcohol can also cause side effects.
A weight loss medication containing orlistat. This medication is used to treat obesity and help you lose weight.
Alli, Xenical, Xenical Alli
Orlistat is a lipase inhibitor. This medication works by blocking an enzyme called lipase that breaks down fats in your diet. By inhibiting this enzyme, orlistat helps break down fats into smaller pieces that can be absorbed into your body. Orlistat works by inhibiting the absorption of fat from your diet, helping you lose weight. You can take this medication with or without food.
Orlistat is used to treat obesity and help you lose weight. It is also used to reduce the risk of heart disease and stroke in patients who are overweight and obese. Orlistat is usually taken once a day, with or without food.
This medication works by blocking the absorption of fat from your diet, helping you lose weight. Orlistat blocks the absorption of fats from the intestines, helping you lose weight. This medication is usually taken once a day, with or without food.
This medication works by inhibiting the absorption of fat from your diet, helping you lose weight.